Nghiên cứu

How has the COVID-19 epidemic affected the risk behaviors of people who inject drugs in a city with high harm reduction service coverage in Vietnam? A qualitative investigation

Tác giả: Trang Thu Nguyen, Giang Thi Hoang, Duc Quang Nguyen, Anh Huu Nguyen, Ngoc Anh Luong, Didier Laureillard, Nicolas Nagot, Don Des Jarlais, Huong Thi Duong, Thanh Thi Tuyet Nham, Oanh Thi Hai Khuat, Khue Minh Pham, Mai Sao Le, Laurent Michel, Delphine Rapoud, Giang Minh Le

Ngày xuất bản: 1 / 2022

Nhà xuất bản: Harm Reduction Journal

Ngôn ngữ: Tiếng Anh

The COVID-19 outbreak disproportionally affects vulnerable populations including people who inject drugs (PWID). Social distancing and stay-at-home orders might result in a lack of access to medical and social services, poorer mental health, and financial precariousness, and thus, increases in HIV and HCV risk behaviors. This article explores how the HIV/HCV risk behaviors of PWID in Haiphong, a city with high harm reduction service coverage in Vietnam, changed during the early phase of the COVID-19 pandemic, and what shaped such changes, using the risk environment framework.

Vấn đề chính: Điều trị nghiện

Từ khóa: COVID-19; Harm reduction; People who inject drugs; Risk behaviors.

Alarming Tuberculosis Rate Among People Who Inject Drugs in Vietnam

Tác giả: Nicolas Nagot, Vinh Vu Hai, Thuy Thi Thu Dong, Oanh Khuat Thi Hai, Delphine Rapoud, Giang Thi Hoang, Catherine Quillet, Khue Pham Minh, Roselyne Vallo, Thanh Tuyet Thi Nham, Joëlle Castellani, Jonathan Feelemyer, Don C. Des Jarlais, Lan Phuong Nguyen, Hoi Van Le, Nhung Viet Nguyen, Luan Nguyen Quang Vo, Huong Thi Duong, Jean-Pierre Moles, Didier Laureillard

Ngày xuất bản: 2 / 2022

Nhà xuất bản: Open Forum Infectious Diseases

Ngôn ngữ: Tiếng Anh

Vấn đề chính: HIV, Lao, Sốt rét Điều trị nghiện

Từ khóa: Drug users, epidemiology, prevalence, risk factors, tuberculosis

A cohort study revealed high mortality among people who inject drugs in Hai Phong, Vietnam

Tác giả: Vu Hai Vinh, Roselyne Vallo, Hoang Thi Giang, Duong Thi Huong, Khuat Thi Hai Oanh, Pham Minh Khue, Nham Thi Tuyet Thanh, Catherine Quillet, Delphine Rapoud, Laurent Michel, Philippe Van de Perre, Jonathan Feelemyer, Jean Pierre Moles, Amandine Cournil, Don Des Jarlais, Didier Laureillard, Nicolas Nagot

Ngày xuất bản: 7 / 2021

Vinh, V. H., Vallo, R., Giang, H. T., Huong, D. T., Oanh, K. T. H., Khue, P. M., Thanh, N. T. T., Quillet, C., Rapoud, D., Michel, L., Van de Perre, P., Feelemyer, J., Moles, J. P., Cournil, A., Des Jarlais, D., Laureillard, D., & Nagot, N. (2021). A cohort study revealed high mortality among people who inject drugs in Hai Phong, Vietnam. Journal of Clinical Epidemiology, 139, 38–48. https://doi.org/10.1016/j.jclinepi.2021.07.007

Abstract

Objective: To estimate the residual mortality rate among people who inject drugs (PWID) in a Low-Middle Income Countries context where the HIV epidemic has been controlled and methadone coverage is high.

Study design and setting: PWID from Haiphong, Vietnam, were recruited through three annual respondent-driven sampling surveys that fueled two cohorts of PWID with HIV (n = 761) and without HIV (n = 897), with bi-annual follow-up. Presumed causes of death were ascertained from medical records and/or interviews of participants family.

Results: Among the 1658 participants with a median follow-up of 2 years, 67 and 36 died in the HIV-positive and HIV-negative cohort, respectively, yielding crude mortality rates of 4.3 (95% Confidence interval (CI): 3.3-5.4) per 100 person-years of follow-up (PYFU) and 1.9 (CI: 1.4-2.6) per 100 PYFU. In the HIV-positive cohort, in which 81% of participants had undetectable viral load, the two main causes of death were tuberculosis and HIV-related diseases. In the HIV-negative cohort, the two main causes of death were liver-related diseases and overdose. In a time-dependent multivariable model, "unsuppressed viral load" was associated with increased risk of mortality, whereas "being on methadone" or "being employed" was associated with a lower risk.

Conclusion: Despite a very successful HIV and methadone program, the mortality remains high among PWID in Vietnam, largely due to curable infectious diseases such as tuberculosis and viral hepatitis.

Keywords: HIV; Mortality; People who inject drugs; Tuberculosis; Viral hepatitis.

Vấn đề chính: Điều trị nghiện

The methamphetamine epidemic among persons who inject heroin in Hai Phong, Vietnam

Tác giả: Don C. Des Jarlais, Jonathan Feelemyer, Kamyar Arasteh, Duong Thi Huong, Khuat Thi Hai Oanh, Pham Minh Khue, Hoang Thi Giang, Nham Thi Tuyet Thanh, Jean Pierre Moles, Vu Hai Vinh, Roselyne Vallo, Catherine Quillet, Delphine Rapoud, Laurent Michel, Didier Laureillard, Nicolas Nagot, for the DRIVE Study Team

Ngày xuất bản: 7 / 2021

Nhà xuất bản: Journal of Substance Abuse Treatment

Ngôn ngữ: Tiếng Anh

To describe the current methamphetamine (MA) use epidemic among persons who inject heroin (PWID) in Hai Phong, Vietnam, and consider possibilities for mitigating adverse effects of methamphetamine use.

Vấn đề chính: Điều trị nghiện

Using large-scale respondent driven sampling to monitor the end of an HIV epidemic among persons who inject drugs in Hai Phong, Viet Nam

Tác giả: Don C. Des Jarlais ,Kamyar Arasteh,Duong Thi Huong,Khuat Thi Hai Oanh,Jonathan P. Feelemyer,Pham Minh Khue,Hoang Thi Giang,Nham Thi Tuyet Thanh,Vu Hai Vinh,Sao Mai Le,Roselyne Vallo,Catherine Quillet,Delphine Rapoud,Laurent Michel,Didier Laureillard,Jean Pierre Moles,Nicolas Nagot,For The DRIVE Study Team

Ngày xuất bản: 8 / 2021

Nhà xuất bản: PLOS ONE

Ngôn ngữ: Tiếng Anh

To describe the use of large-scale respondent driven sampling (RDS) surveys to demonstrate the “end of an HIV epidemic” (HIV incidence < 0.5/100 person-years) among persons who inject drugs (PWID) in a middle-income country. Large sample sizes are needed to convincingly demonstrate very low incidence rates.

Vấn đề chính: HIV, Lao, Sốt rét Điều trị nghiện